当前位置:首页 >> 农林牧渔 >>

中国综合性艾滋病研究项目


中国综合性艾滋病研究项目
China Integrated Programs for Research on AIDS (China CIPRA)
美国国立卫生研究院国际综合性艾滋病研究计划资助 Comprehensive International Program of Research on AIDS

1

Ou

tline of China CIPRA
? CIPRA: Comprehensive International Program of Research on AIDS ? Sponsor: National Institute of Health, USA ? Corporation: National Center for STD/AIDS prevention and control, China CDC ? Period: July 1, 2002 to June 30, 2007 ? Budget: $15 millions ? Project provinces: Shanxi and Yunnan
2

Overall Goal
? To strengthen the existing HIV/AIDS research infrastructure in China and build the capacity to conduct multidisciplinary research to explore promising strategies for HIV/AIDS prevention, treatment and control.

3

Research Group
? The China CIPRA project is composed of 143 research staffs and 12 international consultants. ? The China CIPRA team is composed of 24 collaborating organizations including 13 domestic research institutes, 2 universities, and 2 hospitals, as well as 5 international universities and 2 research institutions.
4

Research Activity (I)
1. To estimate the prevalence and incidence of HIV-1 infection and to determine risk factors. 2. To evaluate the efficacy of more intensive, theoretically-based HIV skill-focused interventions for HIV+ adults. 3. To study viral and host factors that correlate with transmission of infection and factors that determine disease progression; and identify the immunodominant CTL epitopes and their MHC restricting elements in the most prevalent Chinese HIV subtypes as well as provide reagents for these studies. 5

Research Activity (II) 4. To characterize the clinical presentations of AIDS patients in China, to conduct clinical trials of antiviral drugs; 5. To develop vaccine candidates based on the Chinese prevalent strains and to conduct Phase I and Phase II clinical trials to evaluate its safety, immunogenicity and preliminary efficacy.

6

Research Team of China CIPRA
China CIPRA
P I : Yiming Shao Co-PI : Dexian Zheng , Zunyou Wu Advisor: Yi Zeng

Core A (Administration and training)
Leader: Yiming Shao Co-Leader: Dexian Zheng Zunyou Wu Xiaoyan Zhang

Core B
(Statistical and Data Management) Leader: ShuiGao Jin Co-Leader: Hui Li Yuhua Ruan Consultant: Steve Self

Core C (Central Laboratory)
Leader: Yan Jiang Co-Leader: DeXian Zheng Consultant: Haynes W. Sheppard Huyen Cao

Core D (Primate)
Leader: Fude Fang Co-Leader: QiHan Li XinMing Tu Consultant: Ruth Ruprecht, Harold M.McClure, Xiaofang Yu

Project 1 (Epidemiology)
Leader: Xiwen Zheng Co-Leader: Zunyou Wu Lü Fan Shenghan Lai

Project 2 (Behaviroal Intervention)
Leader: Zunyou Wu Co-Leader and Consultant: Roger Detels Rotheram-Borus Mary Jane

Project 3
(Viral Immune Corrlates of
Transmission and Progression)

Project 4 (Clinical Research)
Leader: Yunzhen Cao Co-Leader: Taisheng Li Linqi Zhang Xiaoping Chen Consultant: David Ho

Project 5
(Development of a novel vaccine against HIV/AIDS in China) Leader: Li Ruan Co-Leader: Yiming Shao Wei He Yichen Lu Xiaofang Yu

Consultant: Sten Vermund
Roger Detels , ShenhanLai

Leader: Yiming Shao Co-Leader: Yunqi Geng Judy Lieberman Kunxue Hong , Xing Hui Consultant: Haynes W.Sheppard Huyen Cao

7

CIPRA Coordinating Committee(CCC) ( )
? The CCC is responsible for supervising the general research direction according to the goals of Chinese AIDS control and prevention effort. It will provide guidance and support for the implementation of the China CIPRA research protocol and schedule. In addition, the committee will translate the experiences and results of the China CIPRA program to help advance AIDS research throughout the country.
8

Scientific Advisory Board (SAB)
? Made up of independent domestic and international experts who are not affiliated with the research team. ? Responsibilities include:
assisting with the planning and implementation of the research protocol; receiving research progress reports on a regular basis; aiding in the resolution of research difficulties encountered; providing an independent assessment on a regular basis of the current status of research project

9

Monitoring Group on Quality Control (MGQC)
? This committee is composed of Chinese and international experts and is in charge of maintaining the quality of data generated from this project. The main responsibility of this group is to supervise the quality of the study based on the overall aims and goals of the China CIPRA plan. They will oversee quality control in the following areas: epidemiology, laboratory techniques, experiment quality, clinical studies, and particular research related to the GCP standards. This group will also evaluate the appropriateness of the consent forms and any pertinent ethical issues. They will scrutinize and provide feedback to the researchers to assure the future quality of the research.

10

Network of China-CIPRA Operational Systems
National Institutes of Health (NIH)

CIPRA Coordinating Committee (CCC)

CIPRA Executive Committee (CEC)

Scientific Advisory Board (SAB)

Study Plan/Protocol Ethic Committee (EC)

Study Implementation (Project and Core Activities) Community Advisory Board(CAB) Monitoring Group on Quality Control (MGQC)

Supervision Action

Inform

Study Population

11

Summary of Progress
? ? ? ? ? Set up the administration structure and research team; Conducted preparation work at Shanxi local sites; Developed research protocols; Created SOPs for CIPRA team (on going); Organized training according to the plan;IRB, GCP, management, research techniques, etc. Some researchers were trained oversea ? Strengthened communication among projects and cores, and communication with international organizations. Created web site and newsletter (electronic/paper version).
12

Training Information Welcome
? ? ? ? Project Management and Coordination Leadership and Organization 2 to 3 month/course advanced course preferred

13

Contact information
Address: 4 Nan Wei Road, Room 510 Xuan Wu District Beijing, China 100050 Tel: 86-10-63045970; ; 63015577 ex. 6510 Fax: 86-10-63045970 E-mail: cipracn@public3.bta.net.cn Website: http://www.chinaids.org.cn/cipra

14

15


相关文章:
第五轮中国全球基金艾滋病项目
第五轮中国全球基金艾滋病项目_教学反思/汇报_教学研究_教育专区。第五轮中国全球...日面向项目地区 在性工作者、男男性行为人群(MSM) 、流动人群、艾滋病病毒感染...
浅谈当今国内艾滋病研究与防治现状
扩大综合干预覆盖面、 扩大抗病毒治疗覆盖面, 加强血液...预防控制项目的工作重点、难点和关键环节, 也是未来...艾滋病社会支持的研究现状及实践评价,中国艾滋病性病...
2015-2020年中国抗艾滋病药市场研究与发展前景预测报告...
2015-2020年中国艾滋病药市场研究与发展前景预测...研究某一行业发展动态、规模结构、竞争格局以及综合 ...c)超过 200 多个研究项目的成功案例 d)研究领域...
2004年中国居民艾滋病常识及态度和行为
2004 年中国居民艾滋病常识及态度 和行为状况研究报告 北京零点指标信息咨询有限责任公司 2004 年 6 月 本项目研究结果专属中华人民共和国卫生部 中华人民共和国卫生...
国内外艾滋病研究进展
国内外艾滋病研究进展 摘要: 艾滋病, 即获得性免疫缺陷综合征, 英文名称 ...1995 年中国艾滋 病感染人数从此前的几百例一下子蹿升到 1567 例,其中绝大...
艾滋病在中国的传播
中国预防医学科学院确诊,他患的是艾滋病胃肠综合...已经有许多流行病学研究显示 , 在中国由妓女传播的...相关的预防工作和治疗项目可能应当马上抵达这个易感群体...
艾滋病的研究性学习报告
艾滋病研究性学习结题报告——高二 研究时间:2012 年 4 月 1 日 研究课题...综合各种资料、第 12,13 天:总 结结题报告 6班 六、调查结果 研究物体 ...
我国艾滋病的现状与对策
还成立了中国性病艾滋病协会、 中国性学会等民间学术团体,具体负责咨询、 研究、...项目, 培训医务和检测人员的任务, 各省、 市设立防治性病艾滋病中心, 确立重点...
中国疾病预防控制中心邵一鸣申报卫生外事工作先进个人...
(3)与 HIV 疫苗设计相关的 HLA 分型和表位作图研究 ,(HLA typing and epitope mapping relative to HIV) (95 万美元) 和(4)中国综合性艾滋病研究项目(...
中国艾滋病治疗药物市场分析报告_图文
中国艾滋病治疗药物市场竞争调研与发展趋势研究报告(2013-2017) 中国艾滋病治疗药物市场竞争调研与 发展趋势研究报告(2013-2017) 中国报告网 出版时间:2013 年 中国...
更多相关标签:
中国研究艾滋病进展 | 中国艾滋病研究成果 | 中国项目可行性研究网 | 中国项目研究网 | 艾滋病最新研究成果 | 艾滋病研究进展 | 艾滋病药物研究成功了 | 艾滋病研究 |